The Walmart Supercenter (#1290) is a central retail anchor for Wilkes County, located at 1801 US Highway 421 in Wilkesboro near the intersection with Addison Avenue. This facility operates daily from 6:00 AM to 11:00 PM, providing a comprehensive range of retail departments including a full grocery store with a bakery and deli, electronics, furniture, apparel, and a garden center.